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Benzylideneanilines, the condensation products of benzaldehyde and aniline derivatives, have enjoyed significant success as optical metal ion sensors due to their ability to form stable metal complexes which exhibit distinct spectral features compared to the unbound compound. However, their use in aqueous media is limited by the hydrolytic susceptibility of the C=N moiety. Hence, an in-depth investigation into the hydrolytic degradation mechanism of a series of 2-aminophenol derived Nbenzylideneanilines was conducted wherein molecular modelling techniques were applied to elucidate the “step-by-step” transformation mechanism of these compounds from a fundamental perspective.
Globally, STEM scientists are the apex of novel innovation and cutting-edge research and development. While, patents are inextricably linked to innovation, research, and development, both undergraduate and graduate STEM students rarely invent, and those that do almost never invent twice. The thesis of this presentation is three-fold: (1) The understanding, value, benefits, and basics of intellectual property (IP) creation and invention are fundamentally missing in STEM curricula; (2) There are few (if any) incentives for STEM researchers to create and file patent applications within the University environment; and (3) Patent filling assistance programs (pro se) provide pro bono outreach and education to applicants. The key tenants of this presentation are reduced to practice as it relates to pro se patent filings of West Indies inspired invention to the United States Patent and Trademark Office (USPTO) in 2021 and 2022. Three examples of West Indies conceived and awarded IP by a lead inventor domiciled in Anguilla, BWI (Patent Nos. 10,934,168, 11,219,255, and 11,298,375). Further, a permanent patent filling, titled: “Innocuous Sterilant using Hemocyanin and Functionalized Fullerenes with Broad-Spectrum Intracellular and Interstitial Microbiocidal and Radical Scavenging Effects for Packaged Matter, Biologics and Organics including Liquids, Gases, Tissue, Organs, Cells, and Limbs with Copper Mediated Oxygenation for Viability and Preservation” is under review and awaiting a first office action offering broad evidence of origination of IP in the West Indies. As case studies for this presentation, two pieces of IP are examined: The permanent patent and a recently filed provisional application that teaches a minimally invasive and unassisted robotic surgical method for atomic scale manipulation of funtionalized nanoparticles to perform high precision “nano surgery”.
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