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In parallel and distributed computing environments, task scheduling, where the basic idea is minimizing time loss and maximizing performance, is an absolutely critical component. Scheduling in these environments is NP-hard, so it is important that we continue to search and find the most efficient and effective ways of mapping tasks to processors. One such effective approach is known as Ant Colony Optimization (ACO). This popular optimization technique is inspired by the foraging behavior of ants in their colonies to find the shortest paths between their nests and food sources.
Benzylideneanilines, the condensation products of benzaldehyde and aniline derivatives, have enjoyed significant success as optical metal ion sensors due to their ability to form stable metal complexes which exhibit distinct spectral features compared to the unbound compound. However, their use in aqueous media is limited by the hydrolytic susceptibility of the C=N moiety. Hence, an in-depth investigation into the hydrolytic degradation mechanism of a series of 2-aminophenol derived Nbenzylideneanilines was conducted wherein molecular modelling techniques were applied to elucidate the “step-by-step” transformation mechanism of these compounds from a fundamental perspective.
The malaria epidemic was responsible for about 241 million infectious cases and 627,000 deaths worldwide in 2020.[1] This infectious disease, transmitted by the female Anopheles mosquito, is caused by parasites of the genus Plasmodium namely P. falciparum, P. vivax, P. malariae, P. knowlesi, P. ovale curtisi and P. ovale wallikeri.[2,3] Also, malaria is found predominantly in the highlands of Africa which accounts for more than 90% of infections worldwide. While there has been some success in the treatment of malaria, its eradication has been negatively impacted by insecticide and drug resistance. With emergence of thiosemicarbazone as antimalarial agents, the combination of pyridine and amide or thioamide moieties into one scaffold makes for an interesting target.[4]
Economic development theorists ((Schumpter 1942), (Romer, 1994), (Solow, 1956)) have established the theoretical constructs of scientific and technological developments as foundations to innovative solutions in the form of products, processes and services to long-term socio-economic development and prosperity to high-end economies around the world. It is through the pervasiveness of these innovations within markets which then spurs a sustainable social transformation and long term economic growth within nations.
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