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Oral malodour called halitosis, and commonly referred to as ‘bad breath’, is a socially offensive and discriminating occurrence that requires effective management for health improvement and avoidance of debasing stratification of sufferer. Halitosis has been reported to be prevalent in up to 50% of the general population in the USA, and about 6-23% in China. Between 80% and 85% of halitosis cases are caused by intraoral conditions. Literature on halitosis in Jamaica is either scarce or non-existent. Prior to the COVID-19 pandemic, a common malodour that seemed to be spreading among persons through oral interaction by face-to-face contact with a sufferer was observed among the general populace in Mandeville, Manchester, Jamaica.
The malaria epidemic was responsible for about 241 million infectious cases and 627,000 deaths worldwide in 2020.[1] This infectious disease, transmitted by the female Anopheles mosquito, is caused by parasites of the genus Plasmodium namely P. falciparum, P. vivax, P. malariae, P. knowlesi, P. ovale curtisi and P. ovale wallikeri.[2,3] Also, malaria is found predominantly in the highlands of Africa which accounts for more than 90% of infections worldwide. While there has been some success in the treatment of malaria, its eradication has been negatively impacted by insecticide and drug resistance. With emergence of thiosemicarbazone as antimalarial agents, the combination of pyridine and amide or thioamide moieties into one scaffold makes for an interesting target.[4]
A major challenge facing farmers in Portland, Jamaica is dry weather, especially during the optimal growing season from April through August. During this five-month period Portland suffered from severe dry spells during the years 2014, 2015, 2018 and 2020. A second challenge is the damage to crops and land as well as loss of livestock due to tropical storms or hurricanes and the associated flooding. Portland farmers have suffered losses due to an active hurricane season numerous times and most recently in the years 2004, 2005, 2012 and 2020.
Oral malodour called halitosis, and commonly referred to as ‘bad breath’, is a socially offensive and discriminating occurrence that requires effective management for health improvement and avoidance of debasing stratification of sufferer. Halitosis has been reported to be prevalent in up to 50% of the general population in the USA, and about 6-23% in China. Between 80% and 85% of halitosis cases are caused by intraoral conditions. Literature on halitosis in Jamaica is either scarce or non-existent. Prior to the COVID-19 pandemic, a common malodour that seemed to be spreading among persons through oral interaction by face-to-face contact with a sufferer was observed among the general populace in Mandeville, Manchester, Jamaica.
The majority of scientific discoveries remain confined to dissertations and peer review publications where they remain hidden from their possible industrial applications. Given the challenges offered by current global events like environmental pollution, climate change effects, and diseases, the need for more rapid transmission of scientific discoveries from the realm of postgraduate dissertations and research papers to industrial applications is most critical. Hence, the need for a clear road map, allowing the connection of both pure and applied scientific discoveries to their industrial applications is obvious. Of course, for this to be achieved, a clear understanding of the constituent steps of such a process is germane. Hence, this brief workshop aims to map a possible path for achieving the aforementioned central goal, using previous experiences and examples.
In recent years there has been a resurgence in interest in psychedelic assisted psychotherapy (PAP) [1]. Initial scientific research into the utilization of these compounds were eventually suspended due to concerns related to increasing recreational use of psychedelics and their association with the rise of the “counterculture movement” in the United States [2]. However, the use of psilocybin and other psychedelics have shown promise in the treatment of mental illnesses. The efficacy of this modality of treatment has been demonstrated through clinical trials and other studies in the management of a number of mental illnesses, including some treatment resistant cases [3].
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