Numerous organic chemicals, either directly manufactured or formed as byproducts of other processes, are released into the environment. Once there, many cause adverse effects on environmental and human systems. Of particular concern are long-lasting impacts from those organic pollutants that remain in the environment for long periods of time. The development of appropriate management strategies to address this problem requires knowledge of the environmental distributions of these pollutants.
The malaria epidemic was responsible for about 241 million infectious cases and 627,000 deaths worldwide in 2020. This infectious disease, transmitted by the female Anopheles mosquito, is caused by parasites of the genus Plasmodium namely P. falciparum, P. vivax, P. malariae, P. knowlesi, P. ovale curtisi and P. ovale wallikeri.[2,3] Also, malaria is found predominantly in the highlands of Africa which accounts for more than 90% of infections worldwide. While there has been some success in the treatment of malaria, its eradication has been negatively impacted by insecticide and drug resistance. With emergence of thiosemicarbazone as antimalarial agents, the combination of pyridine and amide or thioamide moieties into one scaffold makes for an interesting target.
Oral malodour called halitosis, and commonly referred to as ‘bad breath’, is a socially offensive and discriminating occurrence that requires effective management for health improvement and avoidance of debasing stratification of sufferer. Halitosis has been reported to be prevalent in up to 50% of the general population in the USA, and about 6-23% in China. Between 80% and 85% of halitosis cases are caused by intraoral conditions. Literature on halitosis in Jamaica is either scarce or non-existent. Prior to the COVID-19 pandemic, a common malodour that seemed to be spreading among persons through oral interaction by face-to-face contact with a sufferer was observed among the general populace in Mandeville, Manchester, Jamaica.
Economic development theorists ((Schumpter 1942), (Romer, 1994), (Solow, 1956)) have established the theoretical constructs of scientific and technological developments as foundations to innovative solutions in the form of products, processes and services to long-term socio-economic development and prosperity to high-end economies around the world. It is through the pervasiveness of these innovations within markets which then spurs a sustainable social transformation and long term economic growth within nations.
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