Vector-borne diseases have since the 17th century been the leading cause of death by disease more than any other causes combined, even preventing development in the tropics (Gubler 1998). Of all insect vectors, Aedes aegypti proves to be the deadliest as it is the primary vector of the four most notorious vector-borne diseases – chikungunya (chik-V), Zika (Zik-V), dengue fever and yellow fever viruses. Control of the spread of Aedesborne diseases is primarily reliant on the control of the vector responsible for their spread. Traditionally, vector control relied on environmental hygiene and the elimination of breeding sites (Gubler 1998), shifting only in the 1980s to the use of synthetic chemicals in the form of carbamate, organochloride, organophosphate and pyrethroid insecticides (Norris, et al. 2015). However, the evolution of Aedes aegypti resistance to synthetic chemicals have made control of the spread of the vector and its diseases increasingly difficult. This led to the exploration of innovative and alternative methods in the control of Aedes aegypti.
Benzylideneanilines, the condensation products of benzaldehyde and aniline derivatives, have enjoyed significant success as optical metal ion sensors due to their ability to form stable metal complexes which exhibit distinct spectral features compared to the unbound compound. However, their use in aqueous media is limited by the hydrolytic susceptibility of the C=N moiety. Hence, an in-depth investigation into the hydrolytic degradation mechanism of a series of 2-aminophenol derived Nbenzylideneanilines was conducted wherein molecular modelling techniques were applied to elucidate the “step-by-step” transformation mechanism of these compounds from a fundamental perspective.
Loan management is a complex process that coordinates agreements among multiple stakeholders in such a way that each party benefits from the arrangement [2]. At the core of our work there is the Asset Token (ATK) which is a compliant ERC-20 token and used for all financial transactions in our proposed system. With this token in our private blockchain network [1], stakeholders can interact in a digital market. Our work includes a Non-Fungible Vehicle Token (VTK) and represents the physical vehicle. Users has access to the ownership of this NFT which prevents fraudulent transactions.
Science and technology and its application to regional development
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