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SYNTHESIS AND ANTIPLASMODIAL EVALUATION OF PYRIDINE CARBOXAMIDES AND THIOCARBOXAMIDES

The malaria epidemic was responsible for about 241 million infectious cases and 627,000 deaths worldwide in 2020.[1] This infectious disease, transmitted by the female Anopheles mosquito, is caused by parasites of the genus Plasmodium namely P. falciparum, P. vivax, P. malariae, P. knowlesi, P. ovale curtisi and P. ovale wallikeri.[2,3] Also, malaria is found predominantly in the highlands of Africa which accounts for more than 90% of infections worldwide. While there has been some success in the treatment of malaria, its eradication has been negatively impacted by insecticide and drug resistance. With emergence of thiosemicarbazone as antimalarial agents, the combination of pyridine and amide or thioamide moieties into one scaffold makes for an interesting target.[4]

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Day 2
  —  
1:25 pm

Small-RNA Next Generation Sequencing, a Tool for the Discovery of the Virome of Jamaican Crops

Plant viruses are responsible for significant losses in crop production annually. Infections are often exacerbated by mixed infections. One strategy of combatting viral disease spread lies in swift diagnoses so that immediate interventions can be employed to slow or stop their spread. Sweet pepper, hot pepper, and tomato are among the most important cash crops in Jamaica and are constantly threatened by pathogens.

Day 3
  —  
2:55 pm

A Preliminary Investigation into the Local Management of Isolated Bacteria Implicated in Malodour (Halitosis) in Mandeville, Jamaica

Oral malodour called halitosis, and commonly referred to as ‘bad breath’, is a socially offensive and discriminating occurrence that requires effective management for health improvement and avoidance of debasing stratification of sufferer. Halitosis has been reported to be prevalent in up to 50% of the general population in the USA, and about 6-23% in China. Between 80% and 85% of halitosis cases are caused by intraoral conditions. Literature on halitosis in Jamaica is either scarce or non-existent. Prior to the COVID-19 pandemic, a common malodour that seemed to be spreading among persons through oral interaction by face-to-face contact with a sufferer was observed among the general populace in Mandeville, Manchester, Jamaica.

Day 3
  —  
10:40 am

Psychedelic Assisted Psychotherapy - Preparing your Target Using Psychohistoriography: A Jamaican perspective

In recent years there has been a resurgence in interest in psychedelic assisted psychotherapy (PAP) [1]. Initial scientific research into the utilization of these compounds were eventually suspended due to concerns related to increasing recreational use of psychedelics and their association with the rise of the “counterculture movement” in the United States [2]. However, the use of psilocybin and other psychedelics have shown promise in the treatment of mental illnesses. The efficacy of this modality of treatment has been demonstrated through clinical trials and other studies in the management of a number of mental illnesses, including some treatment resistant cases [3].

Day 2
  —  
11:10 am

THE EFFECT OF GRUESOME CRIME SCENES ON THE PERSONAL AND PROFESSIONAL LIVES OF FORENSIC CRIME SCENE INVESTIGATORS IN JAMAICA

Forensic Crime Scene Investigators (FCSIs) are forensic practitioners who are key components to the investigative process within a legal framework. In fact, the criminal justice system considers the scientific evaluation and forensic evidence collection to be the most significant aspect of any criminal investigation and court cases. Despite this, limited literature exists on the psychological effects experienced by FCSIs from processing gruesome crime scenes on a regular basis.

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