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SYNTHESIS AND ANTIPLASMODIAL EVALUATION OF PYRIDINE CARBOXAMIDES AND THIOCARBOXAMIDES

The malaria epidemic was responsible for about 241 million infectious cases and 627,000 deaths worldwide in 2020.[1] This infectious disease, transmitted by the female Anopheles mosquito, is caused by parasites of the genus Plasmodium namely P. falciparum, P. vivax, P. malariae, P. knowlesi, P. ovale curtisi and P. ovale wallikeri.[2,3] Also, malaria is found predominantly in the highlands of Africa which accounts for more than 90% of infections worldwide. While there has been some success in the treatment of malaria, its eradication has been negatively impacted by insecticide and drug resistance. With emergence of thiosemicarbazone as antimalarial agents, the combination of pyridine and amide or thioamide moieties into one scaffold makes for an interesting target.[4]

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Day 3
  —  
11:00 am

Workshop 4: Bench top to the conveyor belt: Steps toward the commercialization of scientific innovations

The majority of scientific discoveries remain confined to dissertations and peer review publications where they remain hidden from their possible industrial applications. Given the challenges offered by current global events like environmental pollution, climate change effects, and diseases, the need for more rapid transmission of scientific discoveries from the realm of postgraduate dissertations and research papers to industrial applications is most critical. Hence, the need for a clear road map, allowing the connection of both pure and applied scientific discoveries to their industrial applications is obvious. Of course, for this to be achieved, a clear understanding of the constituent steps of such a process is germane. Hence, this brief workshop aims to map a possible path for achieving the aforementioned central goal, using previous experiences and examples.

Day 2
  —  
11:10 am

THE EFFECT OF GRUESOME CRIME SCENES ON THE PERSONAL AND PROFESSIONAL LIVES OF FORENSIC CRIME SCENE INVESTIGATORS IN JAMAICA

Forensic Crime Scene Investigators (FCSIs) are forensic practitioners who are key components to the investigative process within a legal framework. In fact, the criminal justice system considers the scientific evaluation and forensic evidence collection to be the most significant aspect of any criminal investigation and court cases. Despite this, limited literature exists on the psychological effects experienced by FCSIs from processing gruesome crime scenes on a regular basis.

Day 3
  —  
10:40 am

Psychedelic Assisted Psychotherapy - Preparing your Target Using Psychohistoriography: A Jamaican perspective

In recent years there has been a resurgence in interest in psychedelic assisted psychotherapy (PAP) [1]. Initial scientific research into the utilization of these compounds were eventually suspended due to concerns related to increasing recreational use of psychedelics and their association with the rise of the “counterculture movement” in the United States [2]. However, the use of psilocybin and other psychedelics have shown promise in the treatment of mental illnesses. The efficacy of this modality of treatment has been demonstrated through clinical trials and other studies in the management of a number of mental illnesses, including some treatment resistant cases [3].

Day 1
  —  
4:00 pm

Opening of Conference Space Orientation and Ice Breaker Activities in the Gather.Town space

Opening of Conference Space Orientation and Ice Breaker Activities in the Gather.Town space

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