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SYNTHESIS AND ANTIPLASMODIAL EVALUATION OF PYRIDINE CARBOXAMIDES AND THIOCARBOXAMIDES

The malaria epidemic was responsible for about 241 million infectious cases and 627,000 deaths worldwide in 2020.[1] This infectious disease, transmitted by the female Anopheles mosquito, is caused by parasites of the genus Plasmodium namely P. falciparum, P. vivax, P. malariae, P. knowlesi, P. ovale curtisi and P. ovale wallikeri.[2,3] Also, malaria is found predominantly in the highlands of Africa which accounts for more than 90% of infections worldwide. While there has been some success in the treatment of malaria, its eradication has been negatively impacted by insecticide and drug resistance. With emergence of thiosemicarbazone as antimalarial agents, the combination of pyridine and amide or thioamide moieties into one scaffold makes for an interesting target.[4]

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Day 2
  —  
10:50 am

A Dietary Risk Exposure Assessment of Pesticide Residues found in Commonly Consumed Foods in Trinidad and Tobago

Pesticide usage in agriculture has occurred for centuries and led to significant positive outcomes in food production and noticeable reduction in crop losses. However, pesticide usage on food crops often results in the presence of toxic pesticide residues on food produce, which is the main route of exposure to pesticides in humans. The toxicity of the pesticide residues can potentially cause debilitating effects to major human organs and body systems. Pesticide residue analysis addresses the issue of pesticide residues in foods by screening and quantifying the levels of pesticides in food commodities.

Day 4
  —  
9:40 am

A token-based smart contract management (TSM) DApp for vehicle loans

Loan management is a complex process that coordinates agreements among multiple stakeholders in such a way that each party benefits from the arrangement [2]. At the core of our work there is the Asset Token (ATK) which is a compliant ERC-20 token and used for all financial transactions in our proposed system. With this token in our private blockchain network [1], stakeholders can interact in a digital market. Our work includes a Non-Fungible Vehicle Token (VTK) and represents the physical vehicle. Users has access to the ownership of this NFT which prevents fraudulent transactions.

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